兔抗CDC2(Phospho-Ser124)多克隆抗体

Background:

CDC2 is a member of the CDC25 family of phosphatases. CDC2 is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC2 is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC2 is an oncogene, although its exact role in oncogenesis has not been demonstrated.

Applications:

WB

Name of antibody:

CDC2(Phospho-Ser124)

Immunogen:

Peptide sequence around phosphorylation site of Serine 124 (S-H-S(p)-D-S) derived from Human CDC2.

Full name:

cell division cycle 2

Synonyms：

CDC22

SwissProt:

P30304

WB Predicted band size:

59 kDa

WB Positive control:

293 cells lysates with UV

WB Recommended dilution:

500-1000